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Description
Hypoxia-inducible factor 1 upregulation of both VEGF and ANGPTL4 is required to promote the angiogenic phenotype in uveal melanoma
[PubMed 24429007] 3330
(3) additional details on how potential tools map to the individual drivers, as well as best practices
KTX-1001, a selective NSD2 inhibitor, has been FDA-approved for clinical trials since 2022 and is being studied in a phase I trial to treat patients with R/R MM (NCT05651932)
