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In addition, it has been demonstrated that ROS are also actively involved in the formation of NETs [109], autophagy [110,111,112], chemoattraction and activation of the inflammasome [113,114,115], programmed cell death of infected reservoirs [116, 117], antigen presentation, T-helper cell activation and lymphocyte proliferation [118,119,120,121]

I'm sure you'll notice the change in the skin condition

Beyond direct disruption of membrane lipids, some TCM compounds interfere with membrane-bound proteins and enzymes essential for fungal viability

The proposed mechanisms include activation of the hypothalamicpituitaryadrenal (HPA) axis and the sympathetic nervous system, leading to altered cytokine profiles and immune dysregulation