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To effectively intervene in oxidative stress damage within hypoxia-related pathological processes, the core strategy targeting the HIF pathway focuses on regulating the generation and homeostasis of pathological ROS, rather than solely addressing hypoxia adaptation itself

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10.3109/1354750X.2012.715672 [DOI] [PMC free article] [PubMed] [Google Scholar] Gao B., Doan A., and Hybertson B.M
