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Wang, P., Lombi, E., Zhao, F.-J., & Kopittke, P

The key inputs for a Purple Book-anchored IP valuation model include the first licensure date, the reference product exclusivity expiration, the composition-of-matter patent expiration on the biologic molecule, the formulation and manufacturing process patent expiration dates, the number of aBLA filers and their anticipated timelines, and the interchangeability designation status of any approved biosimilar

ONE 3 , e2565 (2008)

--- The Bottom Line The 87.5% responder rate at 12 months is a meaningful data point
