lysosome glutathione Ferroptosis regulation in Lysosomal iron and cathepsin B contribute to ferroptotic cell death. Lysosomal cyst(e)ine can be mobilized to maintain synthesis and glutathione peroxidase 4 activity, thereby limiting lipid peroxidation Toxicity of Glutathione-Binding Metals: A
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We treated PIK3CA -MT colorectal cancer cells with aspirin in combination with V-9302 under normoxic (20% O 2 , NO) and hypoxic (1% O 2 , HY) conditions
