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Studies have demonstrated that PQQ enhances the activation of key regulators involved in mitochondrial biogenesis and fat metabolism, such as peroxisome proliferator-activated receptors alpha and gamma (PPAR-, PPAR-) and peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1) [38,39]

Most patients have reported that their results lasted anywhere from six months to one year before seeking additional treatment for skin maintenance

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