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Norman PH, Vaporciyan AA, Rice DC , Correa AM
It can inhibit a key step of the folate cycle (at the level of 5-methyltetrahydrofolate), leading to the accumulation of AICAR a natural analog of AMP that potently activates AMPK

I have lots of different hats that I wear, and there are three really important ones that I'm going to talk through today
In addition, macrophages and NK cells have an increased capacity for phagocytosis, chemotaxis and cytokine/chemokine secretion (4, 51, 55)
