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The same study also found a median lethal dose above 5,000 mg/kg, prompting the authors to conclude that bitter leaf is safe for human consumption (Olowokere and Olajide, 2013)

[DOI] [PubMed] [Google Scholar] 5.Sul YH, Lee JY, Kim SH, Ye JB, Lee JS, Yoon SY, Choi JH

Extended analysis of path data from mutant mice using the public domain software Wintrack

Gemfibrozil attenuated amyloid burden as well as neuroinflammation and improved the memory in AD mouse models through activation of PPAR-alpha in a recent study [56], but our study was probably underpowered for this comparison
