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Drug discovery programs have identified CHE as the main antitumor drug candidate

This reaction is catalysed by the enzyme folate conjugase on the brush border of enterocytes in the proximal small intestine 887,888

doi: 10.1016/j.jfca.2020.103615 138 SchiavonM.LimaL

doi: 10.1097/SHK.0000000000000221
