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Adding one compound at a time allows attribution of any issues to the correct substance

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Scrutinizing the Therapeutic Potential of PROTACs in the Management of Alzheimers Disease

T cell transfer model (IL-23 driven): Transfer of naive CD4 + CD45RB hi T cells into immunodeficient mice results in IL-23-dependent colonic inflammation which mimics the T cell-driven immune response against intestinal antigens observed in human IBD (106)
