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10.1016/j.jhep.2020.04.038 132 SoutoJ
This deficiency can stem from various causes, such as impaired gastric absorption due to factors like gastrectomy, bariatric surgery, and pernicious anemia (PA), impaired intestinal absorption from conditions like ileal resection and chronic pancreatitis, decreased intake, hemolysis, HIV, and drug-induced effects, such as from alcohol, proton pump inhibitors, and metformin
Heat exposure Temperatures above 86 degrees Fahrenheit (30 degrees Celsius) accelerate degradation of both the peptide and the B12
