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Periodic treatment breaks are commonly recommended to prevent receptor adaptation and ensure continued responsiveness
Clinical trials confirmed no IGF-1 elevation and no negative impact on glucose metabolism, even during 24-week treatment periods

Ramada MHS, Brand GD, Abro FY et al (2017) Encrypted antimicrobial peptides from plant proteins

The simultaneous application of probiotics and dietary interventions is likely to be a safe and effective adjuvant therapy but its use in the clinic has to address issues of formulation standardization, patient suitability, and long-term safety
