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Meanwhile, 3-BP suppresses lactate production by inhibiting glycolysis, which not only repolarizes M2-type tumor-associated macrophages toward the M1 phenotypes and suppresses regulatory T cell (Treg) infiltration, but also alleviates cGAS lactylation to enhance cGAS activity and amplifying STING-mediated immune responses

Consuming GSH-containing meals may help in solving the problem of low GSH levels

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Results Patients with detectable levels of urolithin in serum and stool and a higher abundance of urolithin-related microbiota had a better outcome