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doi: 10.1001/jama.282.16.1530

However, due to lifestyle factors such as limited sun exposure and dietary insufficiencies, many individuals experience Vitamin D deficiency, which can manifest as fatigue, depression, and weakened immune response

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2.1.1 Cell surface expression of human CD38 Extracellular CD38 is a type 2 transmembrane molecule, approximately 46 kDa in size, featuring a short cytoplasmic tail that grants high mobility within the liquid bilayer, facilitating the formation of soluble forms of CD38 ( Figure 1 )