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These tiny protein fragments are making a big difference for people struggling with injuries that just won't heal

There is a dynamic interplay of pulsatile GHRH and somatostatin secretion: Via crosstalk : GHRH neurons receive inhibitory inputs from somatostatin neurons, whilst somatostatin neurons receive direct stimulatory inputs from GHRH neurons Via synergistic actions on somatotrophs : Pre-exposure to somatostatin enhances GHRH-stimulated secretion of GH (457)

Some see it as a promising compound, while others are skeptical due to limited human trials

The prevailing model is that GHR exists as an inactive dimer and a single molecule of GH binds to two GHR molecules