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doi: 10.1093/alcalc/agaa082

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From the experimental results of example 1 and comparative examples 1 and 2, it can be seen that: the invention takes 7 th-8 th amino acid of a Cagrilintide sequence as pseudo-pro dipeptide Fmoc-Ala-Thr (pro-me-me) -OH, takes 10 th-11 th amino acid of the Cagrilintide sequence as pseudo-pro dipeptide Fmoc-Ala-Thr (pro-me-me) -OH, takes 21 st-22 th amino acid of the Cagrilintide sequence as pseudo-pro dipeptide Fmoc-Ser-Ser (pro-me-me) -OH, and has synergistic effect on improving the purity and yield of Cagrilintide

Before using each dose, take the vial out, prepare your injection, and return the vial to the fridge promptly