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Additionally, the changes in the function, structure, and chemical processes of fear learning and memory circuits are closely associated with the development of PTSD and also pose considerable challenges for its treatment (Harnett et al., 2020)

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According to the studies, though oral administration and topical formulations provides a significant but variable decrease in melanin , intravenous (IV) glutathione offers a rapid reduction in melanin levels, but this speed comes with serious safety concerns , including risks of anaphylaxis and liver toxicity ( hepatotoxicity )

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