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Pegilodecakin, acting as an IL-10 receptor agonist, exhibited a notable 43% ORR in NSCLC patients when combined with nivolumab or pembrolizumab [359]
Used casually, without the right preparation, equipment, and oversight, it can create confusion and sometimes aggravation
One study reported that the percentage of senescent cells in sWAT isolated from older mice (24 months) was almost tenfold that of younger mice (2 months) [33], suggesting that the percentage of senescent sWAT cells is a hallmark of aging [3]
