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In addition, high-salt diets have led to histologically detectable intestinal inflammation in mice models, as confirmed by goblet cell depletion, ulceration, erosion, and destruction of the mucosal layer (Aguiar et al

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This has led to extensive research on its oral bioavailability and efficacy, particularly for gut-related issues but also for systemic healing

the change in the number of nocturia episodes per 24 hours was -21.7 (p=0.001) and -1.51.8 (p=0.003) and the mean voided volume improved from 95 to 176 mL, and from 99 to 174 mL in those with and without nocturnal polyuria, respectively