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Description
Plasma and red blood cells from PV patients showed significantly higher levels of MDH and reduced plasma levels of antioxidant vitamins compared with healthy controls
In the next experiment, buthionine sulfoximine (BSO, 10mM), the inhibitor of gammaglutamylcysteine synthetase was added during 24 hours to A549 cell culture (Figure 4)
They reported their discovery and identified the condition as the result of a third cell attaching to a pair of chromosomes at chromosome 18 (trisomy 18)
2017;8:e2716
