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doi: 10.1021/ac4021775

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Excess lipid availability increases mitochondrial fatty acid oxidative capacity in muscle: evidence against a role for reduced fatty acid oxidation in lipid-induced insulin resistance in rodents

Studies in mice demonstrated that a short course of MOTS-c treatment completely reversed age-related insulin resistance in old muscles after one week of MOTS-c administration, older mices muscles responded to insulin as effectively as those of much younger mice
