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Retatrutide is an investigational triple hormone agonist (GLP-1, GIP, glucagon) showing promising early results for obesity and type 2 diabetes, while tirzepatide is an FDA-approved dual agonist (GLP-1, GIP) available for use today
The experiments were assessed by observers blinded as to the treatment
Science 332 , 220224 (2011)
To assess binding of FITC-z13 to CNGB3, we transfected HeLa cells with a mammalian expression vector encoding a CNGB3MYC fusion protein or with control empty vector
