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TRPA1 deficiency and antagonism are also able to reduce hypoxia-induced painful dysesthesia, similarly to ROS scavengers (So et al., 2016), and attenuate cold hypersensitivity caused by diabetic peripheral neuropathy (Hiyama et al., 2018)
Strandwitz P
Finally, we assessed possible DNA damage, including double-strand breaks, by measuring the -H2AX, a phosphorylated variant of histone H2A, as a marker
GSH manifests in two forms, mercaptan reduction (GSH) and disulfide oxidation (GSSG)
