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Description
Visible changes in tone and firmness appear at 4 to 8 weeks
[DOI] [PMC free article] [PubMed] [Google Scholar] 17.Aksoy P, White TA, Thompson M, Chini EN
We have shown previously that sirtuins SIRT1 and SIRT3 have anti-fibrotic function, and their decreased tissue expression observed in skin biopsies from SSc patients, might directly contribute to the persistence of fibrosis 28,29
It is integral to collagen biosynthesis, immune function, and the neutralisation of free radicals
