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[29] Notably, excessive amounts of nutrients like palmitate and glucose induce ROS generation from NOX4 in adipocytes, resulting in insulin resistance throughout the body

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In other words they supply a different type of molecule, like NMN (nicotinamide mono nucleotide) or NR (nicotinamide riboside) which are not as impactful because our cells need to spend energy to convert these precursors to manufacture into NAD+
