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Description
DEMETER2 (for RNAi) and CERES (for CRISPR) scores express how lethal is a knockdown or knockout, with highly negative values indicating stronger dependency of that gene

SIRT1, sirtuin 1 (a protein involved in cellular stress resistance and metabolic regulation)

Because it is the most powerful antioxidant in our organism, it is often referred to as the "mother of all antioxidants"

Huster et al
