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A meta-analysis of 26 RCTs (n=3,864) found that NAC (typically 600 mg twice daily) reduced the incidence of contrast-induced nephropathy by 40% (OR 0.60, 95% CI 0.44-0.81) (Gonzales et al., BMC Med, 2007) [67]
MDA levels showed a dose-dependent decrease in the LT1 and LT2 groups, whereas lobetyolin administration resulted in a dose-dependent increase in GSH levels and SOD activity
