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Description
This review provides an overview of the current knowledge of these new preservation strategies by machine perfusions and pharmacological interventions at different timing possibilities: in the organ donor, ex-vivo during perfusion machine reconditioning or after implementation in the recipient

Common side effects may include vein irritation, bruising at the injection site, or allergic reactions

A summary of the whole procedure is detailed in Figure 11

Increased cystine uptake, via the increased expression of the SCL7A11 transporter, has been shown to contribute to changes in the epigenome