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In ALS, reduced astrocytic EAAT2 levels and altered microRNA regulation (e.g., increased miR-218 and decreased miR-124a) result in the accumulation of EAAT2-derived toxic species, accumulation of glutamate, and motor neuron degeneration

Transcription Factor ATF3 Mediates the Radioresistance of Breast Cancer

10.1016/j.cell.2013.02.022
