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For example, copper provides the catalytic activity for the antioxidant enzyme copper-zinc superoxide dismutase (CuZnSOD), while zinc plays a critical structural role
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Therefore, the spectrum of iron metabolism alterations in individuals with MHF ranges from minor biochemical changes to tissue iron accumulation, which might lead to iron-related organ damage 14

10.1038/srep23229 [DOI] [PMC free article] [PubMed] [Google Scholar] 27.De Geyter C
