hepatic glutathione synthesis Two-step enzymatic reaction of synthesis. The first step is Glutathione in the Brain |

Thomson MJ Auranofin: Repurposing an Old Drug for a Golden New Age

Thermodynamically, two processes can occur once the -GCL is formed: it may form GSH when it combines with glycine, acting as GSH synthetase (GS, EC 6.3.2.3), or it may interact with the -glutamyl cycle transferase to form 5-oxo-L-proline and L-cysteine

doi: 10.1016/j.jpeds.2015.09.076

It is the intention of the present invention to ameliorate the damage from both cytokine release and oxidation stress at the cell level, stabilize membranes at both the cell and systemic level, and modulate the release of cytokines to moderate the damage from these mechanisms that result in the morbidity and mortality from viral infection such as HHV-6