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Among the ROS, hydroxyl is the most reactive radical, which reacts with lipids, proteins, nucleic acids, and carbohydrates

doi:10.1089/ten.tea.2011.0543 120

[18] Bravo L

GSK-3 is a key regulator of glycogen metabolism that inhibits glycogen synthase, as well as being a regulator of insulin signaling, cell fate specification in embryo development, and cell cycle and apoptosis (reviewed in [293, 294])
