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RNAseq library preparation To generate BT474 persister cells for RNAseq, BT474 cells were plated in five 15 cm tissue culture plates per replicate, for three replicates, and were allowed to reach 75% confluency before being treated with 2 M lapatinib for nine days

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Some drugs also have immunogenicity and allergy risks

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Therefore, we regard our ITC data as relative measurements of both SAM binding and conformational changes

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10.1016/j.trsl.2006.12.002 122 SemlowD

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