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Microbiol 2017, 2, 14801484
Encoded by mitochondrial DNA, MOTS-c acts as a cellular messenger that helps regulate energy metabolism, glucose utilization, and stress adaptation
Glucose induces sensitivity to oxygen deprivation and modulates insulin/IGF-1 signaling and lipid biosynthesis in Caenorhabditis elegans
As a result, partially lipolyzed TRLs, known as remnant TRLs, become enriched in both free and esterified cholesterol
