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Construction of the Clinical Nomogram Application and Drug Targeting Based on LRG Signatures From the GSE21359 discovery dataset of the COPD patients and the control samples, a nomogram integrated with the expression levels of key genes CBR1 and PRDX1 was constructed to quantify their clinical utility in predicting COPD risk (Figure 5A)

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Mechanism and regulation of NLRP3 inflammasome activation

Keap1-KDC domain (327-611) and SOD1 FL proteins were purified and provided by a collaborator as reported 100,101