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The activation of IDO1 activity requires a one-electron reduction of the hemefrom the ferric (Fe III ) state to the ferrous (Fe II ) statefacilitating the binding of O 2 and L-Trp to the ternary complex [135]
Acknowledgments This study constituted part of Aurora Almadoris dissertation for her Ph.D
Cytokine 43, 374379
Plant Physiol 141(1):288298 Li Y, Heaton AC, Carreira L, Meagher RB (2006b) Enhanced tolerance to and accumulation of mercury, but not arsenic, in plants overexpressing two enzymes required for thiol peptide synthesis
