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Although it is an FDA-approved drug for the treatment of urea cycle disorders and has a well-known safety profile, only a few clinical trials have been conducted to investigate its potential for treating neurodegenerative diseases

Despite these positive signals, the clinical evidence remains limited by several key factors: small sample sizes, heterogeneity in probiotic strains, dosages, and administration routes, short follow-up periods, and a primary focus on BV and VVC rather than HPV clearance as the primary endpoint

In cultured cells, H 2 O 2 concentrations of 2050 g/cell exhibit limited cytotoxicity to many cell types

As mentioned above, OLs are rich in iron ions