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It also increases the production of growth factors, such as vascular endothelial growth factor (VEGF), which improves blood flow to the injured area

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Increased NAD levels: Cellular studies show that 5-Amino-1MQ increases NAD concentrations, which improves mitochondrial function and cellular energy efficiency

Furthermore, a critical driver of inflammation involves inflammasome activation in TBI (Liu et al., 2013), and studies in human subjects have shown that inflammasome components are detected in cerebrospinal fluid (CSF) are associated with worse clinical outcomes ( 6.5 Neurodegeneration involving diffuse axonal injury (DAI) Postmortem studies in human subjects have revealed diffuse axonal injury (DAI) as a common neuropathological feature of exacerbated TBI, including Wallerian-like degeneration following injury with white matter atrophy