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One route involves the hydrolysis of cytoplasmic CE by neutral cholesterol esterase and the resulting free cholesterol is mobilized away from the ACAT pool (72,73) and made available for efflux via ABCA1, ABCG1, SR-BI, and aqueous diffusion (Figure 2)

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Significantly, both biofluids exhibited extreme hyperthermophilic behaviour with half denaturation temperatures ( T m ) of 168 C and 180 C, respectively (Table 3 and Fig

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