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Each system possesses distinct advantages and disadvantages, and there is often a trade-off between safety and efficacy (66, 67)

The layered architecture of human skin defines the pathways through which analytes diffuse from the bloodstream into the ISF, establishing both the opportunities and the inherent limits of ISF-based sensing [37,38]

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Development of inhalable quinacrine loaded bovine serum albumin modified cationic nanoparticles: repurposing quinacrine for lung cancer therapeutics