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Description
Potent and selective agonism of the melanocortin receptor 4 with MK-0493 does not induce weight loss in obese human subjects: energy intake predicts lack of weight loss efficacy

Neth J Med

Clinically, a patient on CJC-1295/Ipamorelin might not notice rapid weight loss in a couple of weeks (dont expect the quick drop you might see with a potent appetite suppressant)

Used together, they address energy expenditure and fat accumulation simultaneously
