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In this condition, the mutated receptors have a higher threshold for activation, requiring significantly elevated serum calcium concentrations to inhibit hormone release
This GSH increase in CO23RFLC confers to this strain a clear advantage in counteracting oxidative toxic agents (Fig
However, NKCC2A KO islets also showed increased expression of KCC2, i.e., a furosemide-sensitive and constitutively active K + Cl cotransporter (Payne, 1997
