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(2019b) showed that melatonin ameliorates Al-induced root growth reduction by interrupting nitric reductase- and nitric oxide synthase-dependent nitric oxide production which contributes to cell cycle progression and quiescent centre cellular activity

On the other hand, severe epileptic seizures were induced by the kindling injections of PTZ for 36 days, and the PTZ group had epileptic seizures earlier than the other groups, while high-dose GSPE pre-treatment (200 mg/kg) significantly delayed the time to seizure

Statements Author contributions HH: Writing original draft, Writing review & editing

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