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The effects of NaBPC157 (10 g or 10 ng/kg i.p., i.g.) were investigated in rats in comparison with several reference standards in several experimental ulcer models (48 hour-restraint stress, subcutaneous cysteamine, intragastrical 96% ethanol ulcer tests, NSAIAs-lesions, DNFB (Dinitrofluorhenzene), reflux esophagitis following esophagojejunal termino-lateral anastomosis) (pre-/co-/post-treatment)

Unlike phosphodiesterase-5 (PDE5) inhibitors such as sildenafil, PT-141 works centrally in the brain rather than directly on penile blood vessels

For normal tissue slices, the center of the image was set at x = 0 m

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