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Tranilast slows the progression of advanced diabetic nephropathy
Abnormal collagen deposition and an imbalance between matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) occur (Shao et al., 2025
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As only 1015% of polyphenols seem to be absorbed in the small intestine [100], therefore, most reach the large intestine, where they can suffer the action of microbiota
