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However, the NAC monotherapy arm (600 mg three times daily) showed a trend toward slower decline in forced vital capacity (FVC) that did not reach statistical significance compared to placebo (Martinez et al., N Engl J Med, 2014) [45]

These findings suggest that C-MYC may exert an inhibitory effect on ferroptosis in ovarian cancer cells through NCOA4-mediated ferritin autophagy (104)