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Zhou Q, Zhang Y, Lu L, Zhang H, Zhao C, Pu Y, Yin L
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108,109 The decrease in mitochondrial membrane potential induces PINK1 aggregation and autophosphorylation on the outer mitochondrial membrane, which recruits Parkin to initiate the PINK1-Parkin mitophagy pathway to remove damaged mitochondria
Reduced sympathetic input to the sinoatrial node (SAN), together with enhanced vagal activity, decreases heart rate and stroke volume (SV)
