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Reported observations include: Temporary injection site irritation Mild redness Temporary swelling Local discomfort Mild headache Researchers continue examining long-term biological responses across different laboratory models

Discoid Lupus Erythematosus (DLE) Discoid lupus mainly affects the skin, resulting in inflamed sores and scars

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NNMT inhibitor caused weight loss and reduced adipose tissue mass in DIO mice Since in vitro studies showed 5-amino-1MQ to have high cell permeability, enzyme selectivity, and cell culture efficacy, a sub-chronic (11-day) proof-of-concept in vivo study was conducted to test the effect of NNMT inhibition on obesity in HFD fed mice