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Divicine and isouramil are aglycones that are highly reactive and produce ROS in the blood

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FATP5 promotor polymorphism (rs56225452), representing a putative gain-of-function mutation in the FATP5 promotor, correlated with BMI-dependent hepatic steatosis in males with biopsy proven NAFLD ( n = 103) [20], suggesting that genetic variation may underlie part of the contribution of FATP5 in NAFLD