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These flavocoenzymes ensure the functionality of numerous flavoproteins including dehydrogenases, oxidases, monooxygenases, and reductases, which play pivotal roles in mitochondrial electron transport chain, -oxidation of fatty acids, redox homeostasis, citric acid cycle, branched-chain amino acid catabolism, chromatin remodeling, DNA repair, protein folding, and apoptosis

Evaluation including thyroid ultrasound (TI-RADS), thyroid fine needle aspiration biopsy (FNA) and Bethesda classification system, genetic testing

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Three human serum samples were assayed 20 times in duplicate by three operators to determine precision between assays